Medicinal Mushroom Alcohol Extract vs. Hot Water Extract

By Dr. Markho Rafael

Medicinal mushrooms have been immensely popular in Asia for millennia. Today, Americans are waking up to these powerful nutraceuticals. In the wake of this new awareness follow issues of product quality claims made by competing brands.

All species of medicinal mushrooms appear haunted by this issue. Particularly so, it seems, is red reishi (Ganoderma lucidum), the oldest medicinal mushroom in Traditional Chinese Medicine. Please note, however, that the information in this article applies generally to all medicinal mushroom species.

An obvious caution is to stay away from cheap, mass-produced reishi. It may be merely dried and pulverized. In order to be medicinal, the mushroom cell-wall has to be broken down. Mass-produced reishi may be mostly inert and ineffective.

There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let's sift the data, get the facts straight, and clear up misleading information that is out there.

Following are the three primary ways of creating reishi extracts. Each method yields different medicinal compounds, all of which are shown in scientific studies to have important properties.

1. Water Extraction, Hot (polysaccharides and more)

2. Alcohol/Ethanol Extraction (triterpenoids, etc.)

3. Fermentation (arabinoxylanes, etc.)

The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]

Triterpenoids include a large number of related medicinal compounds whose proven effects include stabilization of blood pressure, cholesterol, and blood clotting. But most importantly, the triterpenoids are the anti-inflammatory compounds of reishi. [1] Inflammation is a serious component in asthma, allergies, arthritis and many more conditions.

And then there are the new and unique medicinal compounds that get created when reishi is fermented. These "secondary metabolites" have their own therapeutic properties, different from the first two groups, including anti-tumor, immune support and blood-sugar balance. [2]

This article is intended to give general guidelines to help you choose an effective reishi product, not to recommend any particular brand. But there are at least two reishi companies on the market which both state only hot water extract is useful while alcohol extracts are of no value.

Of course they do that to promote their own brand. In reality both hot water extract and alcohol extract contain unique medicinal compounds that are all very important.

When looking for the best reishi extract, find one that uses at least the first two extraction methods in combination: Hot Water and Alcohol Extraction. Even better may be a brand that includes all three methods listed.

As a last point, when you look for the best reishi extract, one thing to look at is the form it comes in. For example, any reishi extract that fully dissolves in a water-based liquid such as coffee probably only contains hot water extracted reishi. So while reishi/ganoderma coffee certainly makes for a superbly delicious and healthy cup loaded with polysaccharides, it won't include the important anti-inflammatory triterpenoids.

Surprisingly, though, alcohol tinctures may include both hot water extract and alcohol extract. You will know if the alcohol tincture contains polysaccharides because when the alcohol and hot water extracts are blended, the polysaccharides fall out of solution and the tincture becomes cloudy. (Just shake it before you take it.) A cloudy medicinal mushroom tincture is an indication of high polysaccharide content. Capsules and tablets may be either hot water extract or alcohol extract or both.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnology Annual Review 2007;13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9. - 32378

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